Unfortunately NO! The Dictaphone PowerMic II can only be used on a PC and only within Dragon Medical v10.1 and higher.
After running several test, I found that the PowerMic II will be recognized on MAC and can technically be used as a microphone, however; none of the buttons can be used or programmed.
Verification Source: In-House Testing
If you have any additional questions, please do not hesitate to contact me.